|
1) Elhage R, Gourdy P, Brouchet L, et al. Deleting TCR alpha beta＋ or CD4＋ T lymphocytes leads to opposite effects on site-specific atherosclerosis in female apolipoprotein E-deficient mice. Am J Pathol. 2004; 165: 2013-8
|
|
|
|
2) Infante-Duarte C, Horton HF, Byrne MC, et al. Microbial lipopeptides induce the production of IL-17 in Th cells. J Immunol. 2000; 165: 6107- 15
|
|
|
|
|
|
3) Bettelli E, Carrier Y, Gao W, et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature. 2006; 441: 235-8
|
|
|
|
|
4) Mangan PR, Harrington LE, O'Quinn DB, et al. Transforming growth factor-beta induces development of the T(H)17 lineage. Nature. 2006; 441: 231-4
|
|
|
|
|
|
5) Ivanov, II, McKenzie BS, Zhou L, et al. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17＋ T helper cells. Cell. 2006; 126: 1121-33
|
|
|
|
|
|
6) Laurence A, Tato CM, Davidson TS, et al. Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation. Immunity. 2007; 26: 371-81
|
|
|
|
|
|
7) Chang SH, Park H, Dong C. Act1 adaptor protein is an immediate and essential signaling component of interleukin-17 receptor. J Biol Chem. 2006; 281: 35603-7
|
|
|
|
|
|
8) Qian Y, Liu C, Hartupee J, et al. The adaptor Act1 is required for interleukin 17-dependent signaling associated with autoimmune and inflammatory disease. Nat Immunol. 2007; 8: 247-56
|
|
|
|
|
|
9) Maggi E, Cosmi L, Liotta F, et al. Thymic regulatory T cells. Autoimmun Rev. 2005; 4: 579-86
|
|
|
|
|
|
10) von Boehmer H. Mechanisms of suppression by suppressor T cells. Nat Immunol. 2005; 6: 338- 44
|
|
|
|
|
|
11) Watanabe N, Wang YH, Lee HK, et al. Hassall's corpuscles instruct dendritic cells to induce CD4＋CD25＋ regulatory T cells in human thymus. Nature. 2005; 436: 1181-5
|
|
|
|
|
|
12) Chen W, Jin W, Hardegen N, et al. Conversion of peripheral CD4＋CD25- naive T cells to CD4＋CD25＋ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med. 2003; 198: 1875-86
|
|
|
|
|
|
13) Zhou X, Robertson AK, Rudling M, et al. Lesion development and response to immunization reveal a complex role for CD4 in atherosclerosis. Circ Res. 2005; 96: 427-34
|
|
|
|
|
|
14) Galkina E, Kadl A, Sanders J, et al. Lymphocyte recruitment into the aortic wall before and during development of atherosclerosis is partially L-selectin dependent. J Exp Med. 2006; 203: 1273-82
|
|
|
|
|
|
15) Yilmaz A, Lochno M, Traeg F, et al. Emergence of dendritic cells in rupture-prone regions of vulnerable carotid plaques. Atherosclerosis. 2004; 176: 101-10
|
|
|
|
|
|
16) Erbel C, Sato K, Meyer FB, et al. Functional profile of activated dendritic cells in unstable atherosclerotic plaque. Basic Res Cardiol. 2007; 102: 123-32
|
|
|
|
|
|
17) Buono C, Pang H, Uchida Y, et al. B7-1/B7-2 costimulation regulates plaque antigen-specific T-cell responses and atherogenesis in low-density lipoprotein receptor-deficient mice. Circulation. 2004; 109: 2009-15
|
|
|
|
|
|
18) Ait-Oufella H, Salomon BL, Potteaux S, et al. Natural regulatory T cells control the development of atherosclerosis in mice. Nat Med. 2006; 12: 178-80
|
|
|
|
|
|
19) Vallejo AN, Weyand CM, Goronzy JJ. T-cell senescence: a culprit of immune abnormalities in chronic inflammation and persistent infection. Trends Mol Med. 2004; 10: 119-24
|
|
|
|
|
|
20) Zhang X, Niessner A, Nakajima T, et al. Interleukin 12 induces T-cell recruitment into the atherosclerotic plaque. Circ Res. 2006; 98: 524- 31
|
|
|
|
|
|
21) Smook ML, Heeringa P, Damoiseaux JG, et al. Leukocyte CD40L deficiency affects the CD25(＋) CD4 T cell population but does not affect atherosclerosis. Atherosclerosis. 2005; 183: 275-82
|
|
|
|
|
|
22) Wang X, Ria M, Kelmenson PM, et al. Positional identification of TNFSF4, encoding OX40 ligand, as a gene that influences atherosclerosis susceptibility. Nat Genet. 2005; 37: 365-72
|
|
|
|
|
|
23) Gotsman I, Grabie N, Dacosta R, et al. Proatherogenic immune responses are regulated by the PD-1/PD-L pathway in mice. J Clin Invest. 2007; 117: 2974-82
|
|
|
|
|
|
24) Gotsman I, Grabie N, Gupta R, et al. Impaired regulatory T-cell response and enhanced atherosclerosis in the absence of inducible costimulatory molecule. Circulation. 2006; 114: 2047-55
|
|
|
|
|
|
25) Niwa T, Wada H, Ohashi H, et al. Interferon-gamma produced by bone marrow-derived cells attenuats atherosclerotic lesion formation in LDLR-deficient mice. J Atheroscler Thromb. 2004; 11: 79-87
|
|
|
|
|
26) Buono C, Binder CJ, Stavrakis G, et al. T-bet deficiency reduces atherosclerosis and alters plaque antigen-specific immune responses. Proc Natl Acad Sci U S A. 2005; 102: 1596-601
|
|
|
|
|
|
27) Lord GM, Rao RM, Choe H, et al. T-bet is required for optimal proinflammatory CD4＋ T-cell trafficking. Blood. 2005; 106: 3432-9
|
|
|
|
|
|
28) Branen L, Hovgaard L, Nitulescu M, et al. Inhibition of tumor necrosis factor-alpha reduces atherosclerosis in apolipoprotein E knockout mice. Arterioscler Thromb Vasc Biol. 2004; 24: 2137-42
|
|
|
|
|
|
29) Pryshchep S, Sato K, Goronzy JJ, et al. T cell recognition and killing of vascular smooth muscle cells in acute coronary syndrome. Circ Res. 2006; 98: 1168-76
|
|
|
|
|
|
30) Sato K, Niessner A, Kopecky SL, et al. TRAIL-expressing T cells induce apoptosis of vascular smooth muscle cells in the atherosclerotic plaque. J Exp Med. 2006; 203: 239-50
|
|
|
|
|
|
31) Niessner A, Sato K, Chaikof EL, et al. Pathogen-sensing plasmacytoid dendritic cells stimulate cytotoxic T-cell function in the atherosclerotic plaque through interferon-alpha. Circulation. 2006; 114: 2482-9
|
|
|
|
|
|
32) Michowitz Y, Goldstein E, Roth A, et al. The involvement of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in atherosclerosis. J Am Coll Cardiol. 2005; 45: 1018-24
|
|
|
|
|
|
33) Binder CJ, Hartvigsen K, Chang MK, et al. IL-5 links adaptive and natural immunity specific for epitopes of oxidized LDL and protects from atherosclerosis. J Clin Invest. 2004; 114: 427-37
|
|
|
|
|
|
34) Shimizu K, Shichiri M, Libby P, et al. Th2-predominant inflammation and blockade of IFN-gamma signaling induce aneurysms in allografted aortas. J Clin Invest. 2004; 114: 300-8
|
|
|
|
|
|
35) Heller EA, Liu E, Tager AM, et al. Chemokine CXCL10 promotes atherogenesis by modulating the local balance of effector and regulatory T cells. Circulation. 2006; 113: 2301-12
|
|
|
|
|